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Do 8-15 reps of each set. This is the number that stimulates the greatest increase in fat-burning hormones.
How do you know if you have selected the correct amount of weight to lift? You should struggle start to struggle by the last repetition.
Do 2-4 sets. Do more and you are wasting your time. If you are just beginning to exercise do 2 sets and increase to 4 as you get more fit.